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Hemoglobin
(Hb) Hemoglobin is the major endogenous oxygen-binding molecule, responsible for binding oxygen in the lung and transporting it to the tissues by means of the circulation. Hemoglobin is contained in very high concentration in the red blood cells.
Hemoglobin is a Fe chelate tightly binding one Fe ion in its II oxidation state where it carries the charge 2+. If an oxygen molecule is bound to Hb, Hb is called oxyhemoglobin, if no oxygen molecule is bound it is called deoxyhemoglobin. When hemoglobin is oxidized (i.e. in a hematoma), Fe2+ is transformed into Fe3+. The resulting hemoglobin is then called metoxyhemoglobin (Hb Fe3+).
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 [last update: 2023-11-06 01:42:00]