Cerebrovascular ultrasonography is the best screening tool for the detection of carotid artery stenosis. Transcranial sonography is used in the evaluation of patients with suspected cerebrovascular disease, but a common problem is the attenuation of the ultrasound signal by the skull.
Contrast enhanced ultrasound play a particularly important role in the visualization of the intracranial vessels, and thus improves the accuracy of transcranial Doppler and increases the potential of this technique. The use of microbubbles is helpful for classification of stenosis and for plaque evaluation in patients with poor initial examination. Ultrasound contrast agents avoid misdiagnosing a subtotal stenosis, which is a very important clinical issue.

See also Adventitia, Intima, Periorbital Doppler, and Acoustic Window.

Blood volume per time measured in: cm³/s.
The sonographic detection of blood flow in vascular ultrasound is limited by factors such as tissue motion (clutter), attenuation properties of the intervening tissue, and slow or low-volume flow.

Different flow types in human body:

See also Antegrade, Bi-directional Flow, Velocity, Poiseulles Law, and Venous Ultrasound.

(HVL) The attenuation of ultrasound waves in human tissue is characterized as the half value layer, or the half power distance. Half value layer means the distance the sound beam will travel in a tissue before its amplitude or energy is attenuated to half its original value. Air and lung tissue have extremely short half-power distances and represent severe obstacles to the transmission of acoustic energy.

Two quantities (x, y) are called proportional if they vary in such a way that one of the quantities is a constant multiple of the other, or equivalently if they have a constant ratio (k = y/x). This constant ratio (k) is called the proportionality constant or constant of proportionality of the proportionality relation.

See also Amplitude, Acoustic Power, and Attenuation Coefficient.

(TGC) Time gain compensation is the signal processing control that allows the sonographer to amplify the returning signal from deeper structures in the body. The TGC control compensates for the attenuation of sound waves.