Medical Ultrasound Imaging
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Searchterm 'PESDA' found in 2 articles
1
term [
] - 1 definition [
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PESDA
(Perfluorocarbon exposed sonicated dextrose albumin) PESDA are sonicated dextrose albumin microbubbles containing decafluorobutane gas. PESDA is a sonicated self made contrast agent and not a commercial product.
PESDA microbubbles can be used as a blood pool contrast agent in echocardiography to improve the detection of myocardial perfusion abnormalities.
Drug Information and Specification
RESEARCH NAME
-
DEVELOPER
-
INDICATION -
DEVELOPMENT STAGE
APPLICATION
Intravenous injection
TYPE
Microbubble
Albumin / dextrose
CHARGE
-
Decafluorobutane
MICROBUBBLE SIZE
Mean: 4.7 ± 0.2 μm
PREPARATION
-
DO NOT RELY ON THE INFORMATION PROVIDED HERE, THEY ARE
NOT A SUBSTITUTE FOR THE ACCOMPANYING PACKAGE INSERT!

Perfluorochemicals
Perfluorochemicals are used as microbubble filling gases because of their low solubility in blood and high vapor pressure. Various types of perfluorochemical gases like perfluorocarbon, perfluorobutane, perfluoropropane, and perfluorohexane are used to substitute the air in microbubbles to improve the stability and plasma longevity of the agents. Perfluorocarbons are liquids at room temperature but gas at body temperature. The large molecules of perfluorocarbons have slow diffusion and solubility which increase the enhancement time of the ultrasound contrast agent as compared to air.

See also Filling Gas, and PESDA.
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 [last update: 2023-11-06 01:42:00]