Medical Ultrasound Imaging
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Quantison
Quantison, consisting of air-filled microbubbles with stiff and rigid human serum albumin shells, is an investigational ultrasound contrast agent for the assessment of coronary artery disease.
The stiff shell inhibits the bubbles from oscillating and decrease non-linear scattering. Quantison is capable of long lasting cavity contrast and myocardial opacification using intermittent imaging.
Drug Information and Specification
RESEARCH NAME
AIP101
DEVELOPER
Andaris Ltd. (acquired by Quadrant)
INDICATION -
DEVELOPMENT STAGE
APPLICATION
Intravenous injection
TYPE
Microbubble
Human serum albumin
CHARGE
-
Air
MICROBUBBLE SIZE
-
PREPARATION
Reconstitute with water
DO NOT RELY ON THE INFORMATION PROVIDED HERE, THEY ARE
NOT A SUBSTITUTE FOR THE ACCOMPANYING PACKAGE INSERT!
Sonazoid™
Sonazoid™ is an ultrasound contrast agent (UCA) consisting of stabilized gas microbubbles in an aqueous suspension. Sonazoid™ has overcome the stability problems of first generation USCA and can produce myocardial perfusion images. Myocardial imaging using ultrasound contrast agents provides diagnosis of chronic heart disease and assessment of the coronary arteries and of the coronary blood flow reserve.
Sonazoid™ is taken up by healthy Kupffer cells in the liver and spleen, but break down in high amplitude ultrasound imaging modes such as color Doppler imaging. The bubble rupture produces a transient pressure wave, which results in a characteristic mosaic color pattern from tissues containing the microbubbles (induced acoustic emission). Liver tumors without Kupffer cells will not display the mosaic pattern and can therefore be identified easily.
Drug Information and Specification
RESEARCH NAME
NC100100
DEVELOPER
INDICATION -
DEVELOPMENT STAGE
Development in USA and EU suspended
APPLICATION
-
TYPE
Microbubble
Lipid Stabilized (not disclosed)
CHARGE
Negative
Perfluorobutane
MICROBUBBLE SIZE
-
PRESENTATION
-
STORAGE
-
PREPARATION
Reconstitute with 2mL water
DO NOT RELY ON THE INFORMATION PROVIDED HERE, THEY ARE
NOT A SUBSTITUTE FOR THE ACCOMPANYING PACKAGE INSERT!
SonoRx
From Bracco Diagnostics Inc
SonoRx® is a gas-shadowing reduction agent, used in abdominal ultrasound to enhance the delineation of upper abdominal anatomy. This ultrasound contrast agents is designed to adsorb and displace stomach and bowel gas and should be taken after fasting for at least four hours. Ingestion orally of the simethicone-coated cellulose suspension over 15 minutes in dosages of 200 to 400 ml results in a homogeneous transmission of sound through the contrast-filled stomach.
Bristol-Myers Squibb, under license from ImaRx LLC;; marketed by Bracco Diagnostics Inc, Source: FDA approvals - 11/03/98
Drug Information and Specification
DEVELOPER
INDICATION -
DEVELOPMENT STAGE
APPLICATION
Orally
TYPE
Simethicone-coated cellulose
STORAGE
No special precautions for storage
PREPARATION
Finished suspension
DO NOT RELY ON THE INFORMATION PROVIDED HERE, THEY ARE
NOT A SUBSTITUTE FOR THE ACCOMPANYING PACKAGE INSERT!
Distribution Information
TERRITORY
DISTRIBUTOR
USA, EU
Sonographer
The field of medical imaging offers numerous career opportunities, and one profession is that of a sonographer. Sonographers play a critical role in healthcare by utilizing ultrasound technology to create images of the body's internal structures.
Becoming a Sonographer:
The educational and professional requirements for sonographers can vary from country to country. The duration of these programs can range from one to four years, depending on the country and level of qualification.
The typical path in the United States begins with obtaining a post-secondary education in diagnostic medical sonography from an accredited program. These programs usually result in an associate's or bachelor's degree. Coursework typically covers anatomy, physiology, medical ethics, ultrasound physics, and specialized sonography techniques. Additionally, students gain practical experience through clinical internships in healthcare facilities.
After completing their education, aspiring sonographers can choose to obtain professional certification through organizations such as the American Registry for Diagnostic Medical Sonography (ARDMS) or the American Registry of Radiologic Technologists (ARRT). Certification often requires passing examinations that assess knowledge and competency in specific areas of sonography.
Many countries also have certification or registration requirements for sonographers. These certifications are typically obtained through professional bodies or organizations specific to each country. Examples include the Canadian Association of Registered Diagnostic Ultrasound Professionals (CARDUP) in Canada, the Australian Sonographers Accreditation Registry (ASAR) in Australia, and the Society and College of Radiographers (SCoR) in the United Kingdom.
Job Description:
Sonographers are skilled professionals who operate ultrasound machines and perform sonograms on patients. They work closely with physicians and other healthcare professionals to provide accurate and high-quality diagnostic images. Using sound waves, sonographers capture images of organs, tissues, and blood flow patterns, which are then used by medical practitioners to diagnose and monitor various medical conditions.
Sonographers must have a comprehensive understanding of anatomy, physiology, and sonographic techniques to optimize image quality. They interact directly with patients, explaining procedures, addressing concerns, and ensuring patient comfort throughout the scanning process. Documentation of findings and communication with the medical team are also essential responsibilities.
Some aspect of the job can be demanding, while sonographers often spend long hours on their feet, positioning and maneuvering patients during scans. Dealing with patients who are in pain, anxious, or difficult to scan requires empathy, patience, and excellent interpersonal skills. Sonographers often work in fast-paced environments, juggling multiple patients and procedures throughout the day. Effective time management is essential to ensure that scans are performed efficiently without compromising quality. Adhering to schedules and meeting the demands of the healthcare facility can add to the workload and stress levels.
Salary Outlook:
The salary of a sonographer can vary, based on factors such as experience, specialization, geographic location, and work setting. According to the U.S. Bureau of Labor Statistics, as of May 2021, the median annual wage for diagnostic medical sonographers was $77,740. Sonographers working in specialized hospitals, outpatient care centers, and diagnostic imaging centers tend to earn higher salaries compared to those in physician offices or government facilities. The salary prospects for sonographers outside the United States can vary significantly based on factors such as the country's economic conditions, healthcare system, demand for sonographers, and cost of living.
Future Outlook:
The future outlook for sonographers appears highly favorable. The demand for ultrasound imaging continues to grow due to advancements in medical technology and an aging population. This increasing demand for sonographers is expected to result in good job prospects and potential career advancement opportunities. Monitoring job markets, understanding regulatory requirements, and networking with professionals in international healthcare communities can provide valuable insights into future opportunities.

See also Handheld Ultrasound, Ultrasound Machine, Sonography, Portable Ultrasound Machine, Ultrasound Accessories and Supplies, Environmental Protection and Ultrasound Technology.
Sonography
Sonography [aka: ultrasonography] is a term that encompasses the entire process of performing ultrasound examinations and interpreting the obtained images.
Sonography involves the skilled application of ultrasound technology by trained professionals known as sonographers or ultrasound technologists. These specialists operate the ultrasound equipment, manipulate the transducer, and acquire the necessary pictures for diagnostic imaging purposes. Sonography requires in-depth knowledge of anatomy, physiology, and pathology to accurately interpret the ultrasound images and provide valuable information to the treating physician.
Sonography uses equipment that generates high frequency sound waves to produce images from muscles, soft tissues, fluid collections, and vascular structures of the human body. Obstetric sonography is commonly used during pregnancy. Sonography visualizes anatomy, function, and pathology of for example gallbladder, kidneys, pancreas, spleen, liver, uterus, ovaries, urinary bladder, eye, thyroid, breast, aorta, veins and arteries in the extremities, carotid arteries in the neck, as well as the heart.
A typical medical ultrasound machine, usually a real-time scanner, operates in the frequency range of 2 to 13 megahertz.

See also Musculoskeletal and Joint Ultrasound, Pediatric Ultrasound, Cerebrovascular Ultrasonography and Contrast Enhanced Ultrasound.
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