Medical Ultrasound Imaging
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Temporal Peak Intensity
(ITP) The temporal (instantaneous) peak intensity is the maximum intensity during the ultrasound pulse.
The formula is: P2/rc
P is the instantaneous acoustic pressure, r is the density of the medium and c is the speed of sound in the medium.

See also Temporal Average Intensity (Time Average Intensity).
Thermal Effect
The thermal effect of ultrasound is caused by absorption of the ultrasound beam energy. As the ultrasound waves are absorbed, their energy is converted into heat. The higher the frequency, the greater the absorbed dose, converted to heat according the equation: f = 1/T where T is the period as in simple harmonic motion. Ultrasound is a mechanical energy in which a pressure wave travels through tissue. Heat is produced at the transducer surface and also tissue in the depth can be heated as ultrasound is absorbed.
The thermal effect is highest in tissue with a high absorption coefficient, particularly in bone, and is low where there is little absorption. The temperature rise is also dependent on the thermal characteristics of the tissue (conduction of heat and perfusion), the ultrasound intensity and the length of examination time. The intensity is also dependent on the power output and the position of the tissue in the beam profile. The intensity at a particular point can be changed by many of the operator controls, for example power output, mode (B-mode, color flow, spectral Doppler), scan depth, focus, zoom and area of color flow imaging. The transducer face and tissue in contact with the transducer can be heated.

See also Thermal Units Per Hour and Ultrasound Radiation Force.
Transducer
A transducer is a device, usually electrical or electronic, that converts one type of energy to another. Most transducers are either sensors or actuators. A transducer (also called probe) is a main part of the ultrasound machine. The transducer sends ultrasound waves into the body and receives the echoes produced by the waves when it is placed on or over the body part being imaged.
Ultrasound transducers are made from crystals with piezoelectric properties. This material vibrates at a resonant frequency, when an alternating electric current is applied. The vibration is transmitted into the tissue in short bursts. The speed of transmission within most soft tissues is 1540 m/s, producing a transit time of 6.5 ms/cm. Because the velocity of ultrasound waves is constant, the time taken for the wave to return to the transducer can be used to determine the depth of the object causing the reflection.
The waves will be reflected when they encounter a boundary between two tissues of different density (e.g. soft tissue and bone) and return to the transducer. Conversely, the crystals emit electrical currents when sound or pressure waves hit them (piezoelectric effect). The same crystals can be used to send and receive sound waves; the probe then acts as a receiver, converting mechanical energy back into an electric signal which is used to display an image. A sound absorbing substance eliminates back reflections from the probe itself, and an acoustic lens focuses the emitted sound waves. Then, the received signal gets processed by software to an image which is displayed at a monitor.
Transducer heads may contain one or more crystal elements. In multi-element probes, each crystal has its own circuit. The advantage is that the ultrasound beam can be controlled by changing the timing in which each element gets pulsed. Especially for cardiac ultrasound it is important to steer the beam.
Usually, several different transducer types are available to select the appropriate one for optimal imaging. Probes are formed in many shapes and sizes. The shape of the probe determines its field of view.
Transducers are described in megahertz (MHz) indicating their sound wave frequency. The frequency of emitted sound waves determines how deep the sound beam penetrates and the resolution of the image. Most transducers are only able to emit one frequency because the piezoelectric ceramic or crystals within it have a certain inherent frequency, but multi-frequency probes are also available.
See also Blanking Distance, Damping, Maximum Response Axis, Omnidirectional, and Huygens Principle.
Vascular Ultrasound Contrast Agents
Vascular ultrasound contrast agents are gas microbubbles with a diameter less than 10 μm (2 to 5 μm on average for most of the newer agents) to pass through the lung capillaries and enter into the systemic circulation. Air bubbles in that size persist in solution for only a short time; too short for systemic vascular use in medical ultrasound imaging. So the gas bubbles have to be stabilized to persist long enough and survive pressure changes in the heart.
Most vascular contrast media are stabilized against dissolution and coalescence by the presence of additional materials at the gas-liquid interface. In some cases, this material is an elastic solid shell that enhances stability by supporting a strain to counter the effect of surface tension. In other cases, the material is a surfactant, or a combination of two or more surfactants.
Typically the effective duration of vascular enhancement is a few minutes, after which the microbubbles dissipate. This rather short duration of vascular enhancement makes it easy to perform repeated dynamic studies. Intravenous vascular contrast agents will be used in imaging malignant tumors in the liver, kidney, ovary, pancreas, prostate, and breast. Tumor neovascularization can be a marker for angiogenesis, and Doppler signals from small tumor vessels may be detectable after contrast injection. Contrast agents are useful for evaluating vessels in a variety of organs, including those involved in renal, hepatic, and pancreatic transplants. If an area of ischemia or a stenosis is detected after contrast administration, the use of other more expensive imaging modalities, including CT and MRI, can often be avoided.

See also Acoustically Active Lipospheres.
Wavelength
The wavelength is a unit of relative distance equal to the length of a wave. This could be a light wave, a radio wave, or even a sound wave. For sound waves the formula is:
l=c/f (wavelength = propagation speed/frequency)
In ultrasound imaging is the wavelength the distance between the onset of peak compression or cycle to the next. The wave propagates as bands of compression and rarefaction. One wavelength is the distance between two bands of compression, or rarefaction. Maximum compression corresponds to maximum pressure. The wavelength (see also Angstrom) is important in image resolution.

See also Spectral Reflector.
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